Description
Description: ANAPC13 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 89 amino acids (1-74) and having a molecular mass of 10kDa (Molecular weight on SDS-PAGE will appear higher).ANAPC13 protein is fused to a 15 amino acid T7-tag at N-terminus and is purified by standard chromatography.
Introduction: Anaphase-promoting complex subunit 13 (ANAPC13) is a component of the anaphase promoting complex, which is a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The ANAPC13 protein is evolutionarily conserved and is essential for the integrity and ubiquitin ligase activity of the anaphase promoting complex